Uses/Benefits of 5-MeO DMT; 5-MeO-DMT has been used as a healing agent by South American shamans for thousands of years, partially due to its ability to occasion mystical-type experiences. While research into the drug is still limited, recent studies are backing up these ancient claims.
In a survey of 362 adults, 80% of respondents reported improvements in anxiety and depression after using 5-MeO-DMT, as well as an increase in well-being and life satisfaction. More than that, improvements were directly related to the intensity of the mystical effects felt during the experience. Respondents that had intense mystical experiences also reported higher rates of the experience’s personal meaning and spiritual significance. Uses/Benefits of 5-MeO DMT
The benefits of 5-MeO-DMT have also proven to be enduring—in a recent preliminary study, 42 participants who took 5-MeO-DMT reported an increase in levels of life satisfaction and mindfulness as well as lower levels of depression and anxiety. The effects persisted for four weeks after the initial experience when a follow-up assessment was completed.
A 2019 European study showed that a single inhalation produced sustained enhancement of satisfaction with life, and easing of anxiety, depression, and post-traumatic stress disorder (PTSD)
5-MeO-DMT is being developed and evaluated for potential therapeutic effects in patients with Treatment-Resistant Depression (TRD).
In 2018, researchers also discovered that 5-MeO-DMT is a psychoplastogen, which refers to a compound capable of promoting rapid and sustained neural plasticity.
The Church of the Tree of Life, founded in California in 1971 by John Mann but now defunct, declared the use of 5-MeO-DMT to be a sacrament.
Beckley Psytech in collaboration with King’s College London research the safety and tolerability of intranasal 5-MeO-DMT in healthy subjects, in a phase 1 study. Beckley Psytech CEO Cosmo Feilding-Mellen sees a potential in the short-acting nature of 5-MeO-DMT compared to psilocybin: Uses/Benefits of 5-MeO DMT